OECD/REACH tests

Accredited Testing Laboratories of EL spol. s r.o. have also STATEMENT of GLP COMPLIANCE No. G-017 for non clinical studies of chemical substances (in conformity with GLP according to Law No. 67/2010 Coll. and Directive 2004/10/EC, of the European Parliament and of the Council)

  • Good Laboratory Practice is applied to testing of the health and environmental safety of substances. Business activity is engaged in the non-clinical testing of safety substances in pharmaceuticals, protection of plant products, cosmetic products, veterinary drugs, food and feed and their additives, and industrial chemicals and preparations.
  • The test facility is included in the National GLP Compliance Programme and is regularly reviewed by SNAS (Slovak National Accreditation Service).
Area of expertise

Physical-chemical studies, analytical studies, Environmental toxicity studies on aquatic and terrestrial organisms, Biological testing, Microbiological safety studies, Biodegradability studies.

Type of test items

Drugs and auxiliary substances, Pharmaceutical raw materials, Veterinary medicinal products, Food and feed additives, Cosmetics, Biocides, Pesticides, Soil auxiliary substances, Wastes and extracts, Industrial chemicals and preparations, Detergents.

Areas of applications
  1. Testing of chemical substances and chemical preparations according to the criteria of REACH
    • In accordance to the REGULATION (EC) No 1907/2006 of the EUROPEAN PARLIAMENT and of the COUNCIL of 18th December, 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH)
    • Testing is carried out according to OECD methods:
      • the determination of the physical-chemical properties
      • the determination of ecotoxicological properties (toxicity, degradation, biodegradation)
  2. Control of substances with adverse effects on the environment
    • Analytical testing methods allow analysis of electronic and electrical products in terms of RoHS ( Restriction of the use of Hazardeous Substances) as well as an analysis of SVHC (substances of Very High Concern), PBT and vPvB) in the individual components of the environment
    • Requirements following REACH EP and Council (EC) regulation No. 1907/2006 of 18th December, 2006
  3. Determination of the efficiency of disinfection agents
  4. Determination of stability of products (pharmaceutical raw materials, foodstuffs, cosmetics, chemical preparations) - Stability tests
  5. Testing of biocidal products - Determination of biocidal efficiency (for disinfectants, paints, plasters, etc.)
Commonly performed tests / studies according to OECD / REACH methods
Method
OECD [1]
Method
REACH [2]
Title
Ecotoxicity
201C.3Alga, Growth Inhibition Test
202C.2Daphnia sp. Acute Immobilisation Test
203C.1Fish, Acute Toxicity Test
209C.11Activated Sludge, Respiration Inhibition Test
211C.20Daphnia magna Reproduction Test
Ready Biodegradability
301AC.4-ADOC Die-Away Test
301BC.4-CCO2 Evolution Test (Modified Sturm Test)
301CC.4-FModified MITI Test (I)
301DC.4-EClosed Bottle Test
301EC.4-BModified OECD Screening Test
301FC.4-DManometric Respirometry Test
Inherent Biodegradability
302AC.12Modified SCAS Test
302BC.9Zahn-Wellens/EMPA Test
302C-Modified MITI Test (II)

[1] Organization for Economic Co-operation and Development

[2] COUNCIL REGULATION (EC) No 440/2008 of 30 May 2008 laying down test methods pursuant to Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH)